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Percocet effects


Percocet effects are widespread throughout the body.  Percocet is a Oxycodone derivative used extensively for the around-the-clock management of severe pain.  Percocet has the addiction of acetaminophen to its formulation.  The acetaminophen component acts to fight against fever or generalized increases to body temperature.  The body parts experiencing Percocet are the central nervous system, the gastrointestinal system, and the cardiovascular system.

The Percocet effects on the central nervous system are primarily those of pain relief and depression.  Receptors for Percocet have been found throughout the brain and spinal cord though the exact mechanism of action is unknown.  Percocet effects arise via its direct action on the brainstem respiratory centre suppressing respiratory rate and cough reflex.  At low doses, Percocet has potential to treat excessive cough at doses ineffective for pain relief.  Percocet can lead to addictions through its stimulation of the natural reward system in the brain.

Percocet Effects
Percocet effects

In the gastrointestinal tract, use of the drug will result in are limited to constipation and decreased secretions of digestive enzymes as the main Percocet effects.  Constipation results from reduction in gastric motility and increased muscle tone.  These two Percocet effects reduce propulsion throughout the length of the intestine which is the primary cause of constipation.  Gastric secretions are also limited due to spasm of sphincters controlling their release.


Percocet effects on the cardiovascular system are primarily related to vasodilatation.  Percocet results in histamine release resulting in peripheral vasodilatation causing itchy skin, flushing, red eyes, and hypotension when standing up.


When prescribed and administered properly, the most noticeable Percocet effects are chronic pain relief.  However, this drug is addictive as the Percocet effects are not limited to managing pain so its use should be thoroughly discussed with a licensed medical practitioner.