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Oxycontin Side Effects

Oxycontin side effects are similar its parent drug, Oxycodone.  However, due to its extended release formulation, Oxycontin side effects do have some unique characteristics worth noting.


The serious oxycontin side effects seen in clinical use are similar to side effects seen with any opiod drug.  These include decreased respiratory rate, responsiveness, or arrest, apnea, as well as decreased circulation and heart rate, hypotension, and shock.  Non-serious oxycontin side effects are dose dependant and include constipation, drowsiness, dizziness and nausea, vomiting, itching, headaches, dry mouth, sweating, and muscle weakness.  These oxycontin side effects can usually be minimized if the initiation of dosage begins small, works to larger doses, and the patient’s pain is constantly monitored.

Oxycontin Side Effects
Oxycontin Side Effects

General: accidental injury, chest pain, facial edema (swelling), general feeling of being unwell, neck pain, pain, and allergic reactions

Cardiovascular: migraine, fainting due to hypotension, vasodilation,

Digestive: difficulty swallowing, burping, flatulence, increased appetite, nausea and vomiting, inflammation in the mouth, intestinal blockage

Nervous: abnormal gait, agitation, amnesia, depression, hallucination, seizures, speech disorder, stupor, ringing in the ears, tremor, vertigo, withdrawal syndrome with or without seizures

Respiratory: cough increased, sore throat, voice alteration

Skin: dry skin, peeling skin, rash/hives

Special Senses: abnormal vision, taste perversion

Urogenital: loss of monthly period, decreased libido, difficult/painful when urinating, blood in urine, impotence, urinary retention, urination impaired


Oxycontin side effects related to overdose are much more severe and deadly.  Often overdose occurs with abuse and misuse of oxycontin by ingesting, inhaling, or injecting crushed tables.  Oxycontin side effects related to overdose are worsened when oxycontin is abused during use of central nervous system depressants such as alcohol or other opiods.